- Advanced Centre for Energetic Materials (ACEM)
- Advanced Systems Laboratory (ASL)
- Aerial Delivery Research and Development Establishment (ADRDE)
- Aeronautical Development Establishment (ADE)
- Armament Research & Development Establishment (ARDE)
- Centre For Air Borne System (CABS)
- Centre for Artificial Intelligence & Robotics (CAIR)
- Centre for Fire, Explosive and Environment Safety (CFEES)
- Centre for Military Airworthiness and Certification (CEMILAC)
- Centre for Personnel Talent Management (CEPTAM)
- Combat Vehicles Research & Development Establishment (CVRDE)
- Defence Avionics Research Establishment (DARE)
- Defence Bio-Engineering & Electro Medical Laboratory (DEBEL)
- Defence Electronics Application Laboratory (DEAL)
- Defence Electronics Research Laboratory (DLRL)
- Defence Food Research Laboratory (DFRL)
DRDL is working on several technologies required for the Missiles and Strategic Systems including; Aerodynamics and Airframe Design, Computational Fluid Dynamics, Solid, Liquid, Ramjet and Scramjet Propulsion, Precision Fabrication, Systems Analysis, as well as the Command and Control systems for missile based weapon.